Table 2.

MIC distribution for drugs tested against 1,684 pneumococcal isolates collected in Spain from 1998 through 1999

Antimicrobial agentNo. (%) of inhibited isolates for which the MIC (μg/ml) was:
≤0.0150.030.060.1250.250.512481632≥64
Penicillin710 (42.1)83 (4.9)46 (2.7)83 (4.9)102 (6.1)112 (6.6)182 (10.8)256 (15.2)110 (6.5)0 (0)
Amoxicillin369 (21.9)415 (24.6)88 (5.2)63 (3.7)86 (5.1)99 (5.9)159 (9.4)240 (14.2)79 (4.7)65 (3.9)21 (1.2)
Amoxiclav491 (29.1)313 (18.6)79 (4.7)58 (3.4)87 (5.2)89 (5.3)189 (11.2)217 (12.9)74 (4.4)69 (4.2)18 (1.1)0 (0)
Cefaclor893 (53.0)90 (5.3)57 (3.4)79 (4.7)75 (4.5)180 (10.7)310 (18.5)
Cefuroxime879 (52.2)72 (4.3)57 (3.4)147 (8.7)246 (14.6)249 (14.8)34 (2.0)0 (0)
Cefixime799 (47.4)82 (4.9)64 (3.8)77 (4.6)594 (35.3)68 (4.0)
Cefotaxime1,061 (63.0)226 (13.4)282 (16.7)109 (6.5)5 (0.3)1 (0.1)0 (0)
Erythromycin1,081 (64.2)15 (0.9)0 (0)4 (0.2)13 (0.8)9 (0.5)10 (0.6)122 (7.2)28 (1.7)402 (23.9)
Clarythromycin1,097 (65.1)3 (0.2)10 (0.6)7 (0.4)13 (0.8)4 (0.2)135 (8.0)8 (0.5)407 (24.2)
Azithromycin844 (50.1)86 (5.1)132 (7.8)37 (2.2)6 (0.4)8 (0.5)8 (0.5)124 (7.4)9 (0.5)430 (25.5)
Ciprofloxacin289 (17.2)805 (47.8)470 (27.9)78 (4.6)13 (0.8)29 (1.7)