Table 2.

MICs of β-lactams for C. meningosepticumPINT, E. coli DH10B harboring recombinant plasmid pBS1, and reference strain E. coli DH10B

β-LactamaMIC (μg/ml)
C. meningosepticum PINTE. coliDH10B(pBS1)E. coli DH10B
Amoxicillin2565124
Amoxicillin + CLA6444
Amoxicillin + TZB6442
Amoxicillin + FOX12884
Amoxicillin + MOX64164
Amoxicillin + IPM6424
Ticarcillin2565124
Ticarcillin + CLA6484
Ticarcillin + TZB12844
Ticarcillin + FOX128324
Ticarcillin + MOX128644
Ticarcillin + IPM12844
Piperacillin3281
Piperacillin + CLA1621
Piperacillin + TZB1621
Piperacillin + FOX1621
Piperacillin + MOX3221
Piperacillin + IPM3221
Cephalothin5122562
Cefoxitin3241
Ceftazidime256320.5
Ceftazidime + CLA160.50.5
Ceftazidime + TZB160.250.5
Ceftazidime + FOX1610.5
Ceftazidime + MOX6420.5
Ceftazidime + IPM640.50.5
Cefotaxime6440.12
Cefepime320.50.03
Cefepime + CLA40.030.03
Cefepime + TZB40.030.03
Cefepime + FOX80.060.03
Cefepime + MOX160.060.03
Cefepime + IPM160.060.03
Aztreonam>512160.25
Aztreonam + CLA>5120.120.25
Aztreonam + TZB>5120.250.25
Aztreonam + FOX>5120.250.25
Aztreonam + MOX>5120.50.25
Aztreonam + IPM>5120.250.25
Moxalactam640.250.12
Imipenem320.250.12
  • a CLA, clavulanic acid at a fixed concentration of 2 μg/ml; TZB, tazobactam at a fixed concentration of 4 μg/ml; FOX, cefoxitin at a fixed concentration of 0.1 μg/ml; IPM, imipenem at a fixed concentration of 0.5 μg/ml; MOX, moxalactam at a fixed concentration of 0.05 μg/ml.