Table 1.

MICs for K. pneumoniae clinical isolates Kp 395 and Kp 377 and E. coli strains producing TEM-18, TEM-2, or TEM-3

Strain or β-lactamase producedMIC (μg/ml)a
AMXTICPIPCFTFOXATMCTXCAZ
K. pneumoniae
 Kp 395 (TEM-56)>8,192 (1,024)>8,192 (1,024)>2,048 (16)5124 (4)1 (0.25)0.25 (≤0.06)4 (2)
 Kp 377 (TEM-21)>8,192 (32)>8,192 (16)1,024 (4)2564 (4)16 (0.12)128 (≤0.06)32 (1)
E. coli
 TEM-188,192 (512)1,024 (64)512 (16)168 (8)2 (1)0.25 (0.12)4 (2)
 TEM-38,192 (16)8,192 (32)256 (2)1284 (4)8 (0.5)64 (0.12)32 (0.5)
 TEM-24,096 (16)4,096 (32)512 (2)322 (2)≤0.06 (≤0.06)≤0.06 (≤0.06)0.5 (0.25)
  • a AMX, amoxicillin; TIC, ticarcillin; PIP, piperacillin; CFT, cephalothin; FOX, cefoxitin; ATM, aztreonam; CTX, cefotaxime; CAZ, ceftazidime. The values in parentheses are MICs in the presence of 2 μg/ml of clavulanic acid.