Table 5.

Frequency distributions of GCV IC50s for recent clinical isolates using the ACTG consensus protocol

GCV IC50 (μM)No. of assays with IC50 at each GCV concn
CMV 1aCMV 2CMV 3CMV 4CMV 5CMV 6
 ≤1.5212
>1.5–3.032
>3.0–6.022117
>6.0–12 222
 >12–24 222
 >24–48 2211
 >48–96 4113
>96  11018
Total no. of assays1210b 12121212
Median IC50 22.942.97>9611.314.13>96
No. (%) resistant8 (67)1 (10)11 (92)6 (50)3 (25)12 (100)
  • a CMV 1 to 6 were not plaque purified.

  • b Data not submitted by two laboratories.