Table 2.

Efficacy of FK463 in mouse models of pulmonary fungal infection

A. fumigatus strainInoculum (105CFU)ED50(mg/kg/day)a of:
FK463AMPH-B
TIMM00638.80.35 (0.24–0.51)0.36 (0.24–0.52)
IFM408147.00.26 (0.18–0.36)0.26 (0.18–0.36)
IFM412093.50.51 (0.34–0.75)0.46 (0.32–0.67)
  • a Values in parentheses are 95% confidence intervals.