Table 3.

Mutations in marOR in E. coli marmutants selected with ofloxacin

MutantNucleotide changeMutation
2-AG1001485+1Frameshift
2-AG100b1834+1; Δ1835−1847Frameshift, 13-bp deletion
2-748Δ1610Frameshift
2-748LΔ1800Frameshift
2-748MMΔ1408−142215-bp deletion
2-748SLΔ1835−184713-bp deletion
2-748SSWild type
2-748SM-2Wild type
2-748SM-3Δ1694Frameshift
2T-I1673C→AR77S
2T-IV1609+2Frameshift
2T-VΔ1639Frameshift
2T-VIIΔ1425-144420-bp deletion
2-C1751751G→Aa; Δ1831−1853G103Sa; 23-bp deletion
2-C482Δ1748−175811-bp deletion
2-C71Δ1519Frameshift
  • a Previously shown to be a genotypic variation in marR without loss of repressor activity (25).