Table 1.

Agar dilution MICs for 201 pneumococcal isolates

DrugPenicillin susceptibility of strainaMIC (μg/ml)
RangeMIC50bMIC90c
PenicillinS≤0.008–0.06≤0.0160.03
I0.125–1.00.251.0
R2.0–>8.02.04.0
GAR-936S≤0.016–0.1250.030.125
I≤0.016–0.1250.030.06
R≤0.016–0.1250.060.125
TetracyclineS≤0.06–64.00.2532.0
I≤0.06–64.01.064.0
R≤0.25–128.032.064.0
MinocyclineS≤0.06–16.00.068.0
I≤0.06–16.00.2516.0
R≤0.06–16.04.016.0
DoxycyclineS0.03–16.00.1258.0
I≤0.06–32.00.58.0
R0.125–16.04.08.0
AmoxicillinS≤0.008–0.250.0160.03
I≤0.016–2.00.1251.0
R0.5–4.02.02.0
CeftriaxoneS≤0.008–1.00.0160.03
I≤0.016–2.00.251.0
R0.25–8.01.02.0
ClarithromycinS≤0.016–>128.00.038.0
I≤0.016–>128.00.06>128.0
R≤0.016–>128.01.0>128.0
ImipenemS≤0.008–0.25≤0.0080.016
I≤0.008–0.250.060.25
R0.03–0.50.250.5
MeropenemS≤0.008–0.50.0160.03
I≤0.016–0.50.1250.5
R0.125–2.00.51.0
VancomycinS≤0.06–0.50.250.25
I≤0.06–0.50.250.25
R0.125–0.50.250.25
  • a S, penicillin susceptible; I, penicillin intermediate; R, penicillin resistant.

  • b MIC50, MIC at which 50% of the isolates tested were inhibited.

  • c MIC90, MIC at which 90% of the isolates tested were inhibited.