Table 1.

DHFR and DHPS genotypes of P. falciparumisolates collected before PM-SD treatment in Kilifi, Kenya, between 1997 and 1998a

No. of isolatesGenotypebat indicated codon in:
DHFRDHPS
1085159164436437540581613
4NDNDNDND
1NDNDNDNDMix
7
1Mut
1
1NDNDNDNDND
2Mut
6MutMut
1MixMut
1MutMix
1MutMixMixMut
1MutMutMutMut
3MutMutNDNDNDNDND
1MixMixMut
1MixMix
2MutMut
1MutMutMut
1MixMutMix
1MutMutMix
1MutMutMixMut
2MutMixMut
11MutMutMut
  • a All isolates were collected from patients who were aparasitemic 7 days after treatment.

  • b Mut, mutated; Mix, mixed; —, wild type; ND, not determined. At position 436 of DHPS, the mutated codon is Ala and the mixed codons are Ala and Ser.