Table 3.

Percent identity between the amino acid sequences of class B carbapenem-hydrolyzing β-lactamasesa

β-Lactamase% Identity
VIM-2VIM-1B-IIIMP-1CcrABlaBIND-1CphA-1L-1GOB-1
VIM-190
B-II3235
IMP-1312831
CcrA27272834
BlaB2424322725
IND-1242433282740
CphA-121232619202523
L-111131291191112
GOB-14410121011121318
  • a The origins of the β-lactamases are as follows: VIM-2, P. aeruginosa COL-1; VIM-1, P. aeruginosa VR 143-97 (10); B-II, B. cereus(8); IMP-1, various gram-negative rods, including P. aeruginosa (15); BlaB, C. meningosepticumCCUG4310 (21); IND-1, Chryseobacterium indologenes 001 (2); CcrA, Bacteroides fragilis TAL 3636 (19); CphA-1, Aeromonas hydrophila AE036 (12); L-1, Stenotrophomonas maltophilia IID1275 (25); GOB-1, C. meningosepticum (GenBank accession no. AF90141).