Table 2.

Ethionamide concentration in plasma, ELF, and AC

CompartmentValue for group (n = 10)a:
Men with AIDSMen without AIDSWomen with AIDSWomen without AIDS
Plasma
 2 h1.0 ± 0.71.1 ± 0.50.9 ± 1.00.9 ± 0.4
 4 h0.7 ± 0.30.7 ± 0.30.6 ± 0.50.6 ± 0.2
ELF
 Mean ± SDb 4.6 ± 3.25.5 ± 3.36.2 ± 4.66.2 ± 4.2
 Range1.8–12.01.3–13.51.9–17.42.1–16.7
AC
 Mean ± SD0.5 ± 0.60.5 ± 0.60.3 ± 0.20.2 ± 0.4
 Range 0–1.4 0–1.6 0–0.6 0–1.0
  • a Data are given as means ± 1 SD in micrograms per milliliter. Range data are minimum to maximum values. There was no significant effect of the presence of AIDS or gender or an interaction between AIDS and gender (P > 0.05) on ethionamide concentrations in plasma, ELF, or AC (P > 0.05).

  • b Within each group, concentrations in ELF were significantly greater than concentrations in plasma at 2 or 4 h or in AC (P < 0.05).