TABLE 2

Baseline patient characteristics

CovariateNo. of patients (%) with the characteristic ina:
Overall cohort comparison (n = 165)Propensity score-matched cohort comparison (n = 82)
TZP (n = 88)FEP/MEM (n = 77)P valueTZP (n = 41)FEP/MEM (n = 41)P value
Age [median yr (range)]65 (52, 75)65 (47, 75)0.4168 (59, 78)57 (40, 69)0.012
Male sex50 (57)48 (62)0.5825 (61)26 (63)0.84
Neutropenia3 (3)7 (9)0.2603 (7)0.99
Immunosuppression18 (21)25 (33)0.127 (17)9 (22)0.34
Charlson comorbidity score [median (range)]3 (1, 7)3 (2, 5)0.653 (1, 6)3 (2, 4)0.47
Days to bacteremia (median [range])1 (1, 9)5 (1, 15)0.0021 (1, 6)2 (1, 10)0.11
Renal replacement therapy14 (16)14 (18)0.392 (5)3 (7)0.65
ICU stay30 (34)36 (60)0.00217 (41)15 (37)0.34
Septic shock14 (16)26 (34)0.077 (17)7 (17)1
Pitt bacteremia score [median (range)]1 (0, 3)2 (0, 6)0.0122 (0, 4)1 (0, 3)0.4
Presumed source of infection0.830.6
    Urinary tract19 (22)12 (21)10 (24)8 (20)
    LRTI/VAP12 (14)16 (21)6 (15)8 (20)
    Surgery related/SSTI8 (9)7 (9)5 (12)4 (10)
    Catheter related10 (11)12 (16)3 (7)4 (10)
    Intra-abdominal20 (23)13 (17)10 (24)5 (12)
    Gut translocation7 (8)7 (9)2 (5)5 (12)
    Multiple1 (1)2 (3)1 (2)2 (5)
    Unknown11 (13)8 (10)4 (10)5 (12)
Responsible pathogen0.120.54
    Enterobacter spp.51 (58)52 (68)23 (56)23 (56)
    Serratia spp.24 (27)21 (27)12 (29)15 (37)
    Citrobacter spp.13 (15)4 (5)6 (15)3 (7)
  • a Data are the number (percentage) of patients with the indicated characteristic, unless otherwise indicated (i.e., median number and range). Abbreviations: LRTI/VAP, lower respiratory tract infection/ventilator-associated pneumonia; SSTI, skin/soft tissue infection.