Table 3.

defB gene disruption inS. aureusa

S. aureus strainDisruption targetfmt genotypeTiter (log10 CFU/ml)
30°C43°C
RN4220 lacG fmt+ 9.87.3
RN4220No homology fmt + 9.53.6
RN4220 defB fmt + 9.63.5
VSAU7136 defB Δfmt 8.55.3
VSAU6011 lacG fmtmutant8.74.9
VSAU6011 defB fmtmutant8.84.3
  • a Viable organisms recovered at permissive (30°C) or restrictive (43°C) temperatures.