Table 3.

Susceptibility to FQs of efflux-mediated resistant transformants of S. pneumoniae strain R6

Strain or transformantbMIC (μg/ml) ofa:
NORNOR + RESCIPCIP + RESSPX
SMB9128161621
SOB512881621
R644110.25
R6TrSMB9 324810.25
R6TrSOB5 324810.25
  • a NOR, norfloxacin; CIP, ciprofloxacin; RES, reserpine; SPX, sparfloxacin.

  • b Superscript indicates the genomic DNA donor strain. Tr, transformant.