Table 4.

In vitro poly(A)-directed translation using ribosomes from isogenic strains

StrainIC50 (μg/ml) of compounda:
ERYAZMJOSTELCLXSTB
R60.020.020.20.020.030.15
ML10.080.08>100.040.090.3
Z100.91.2>100.020.30.3
Z10-Spir0.50.8>100.040.60.6
CP10000.070.010.0030.0050.030.1
BM444010780.40.05>10
R60.010.010.20.080.010.3
R6 MSB >10>10>100.150.03>10
  • a Fourteen-membered macrolide: erythromycin (ERY); 15-membered macrolide: azithromycin (AZM); 16-membered macrolide: josamycin (JOS); ketolide: telithromycin (TEL); lincosamide: clindamycin (CLX); streptogramin: streptogramin B (STB).