Table 2.

MICs of macrolide-lincosamide-streptogramin B antibiotics against MSB and ML strains

StrainMIC (μg/ml) of compounda:
ERYCLRAZMJOSTELLINCLXSTASTBPEN
E4010025>100>1000.0112.50.781006.256.25
02J12005012.5>100>1000.0112.50.781003.120.01
117-8915012.5>100>1000.0112.50.78503.120.03
Bu4110012.5>1001000.030.780.0510012.56.25
Sof289b >10025>1001000.10.780.110012.53.12
395>10025>1001000.11.560.110012.51.56
39810025>1001000.030.780.0510012.53.12
404>10025>100>1000.21.560.1>100256.25
407>10025>1001000.051.560.1100256.25
381>10025>1001000.050.390.05100256.25
386>10050>1001000.10.390.1100253.12
387>10050>1001000.10.390.1100251.56
442>10025>1001000.10.780.110012.56.25
BM44186.2512.512.56.253.120.390.0550250.01
ATCC 496190.030.030.10.20.0060.780.05253.120.39
  • a Fourteen-membered macrolides: erythromycin (ERY) and clarithromycin (CLR); 15-membered macrolide: azithromycin (AZM); 16-membered macrolide: josamycin (JOS); ketolide: telithromycin (TEL); lincosamides: lincomycin (LIN) and clindamycin (CLX); streptogramins: streptogramin A (STA) and streptogramin B (STB). PEN, penicillin G.

  • b The MICs for Sof289 are representative of those for six other identical isolates (Bul23, Bul29, Bul34, Bul40, Bul91, and Bul115).