Table 2.

rpoB mutations observed in rifampin-resistant mutants

MutationCodon changeNo. (%) of mutations
S531LTCG→ TTG39 (60.9)
H526YCAC→ TAC6 (9.4)
H526RCAC→ CGC5 (7.8)
H526DCAC→ GAC4 (6.2)
S522LTCG→ TTG4 (6.2)
S531WTCG→ TGG2 (3.1)
H526PCAC→ CCC1 (1.6)
D516VGAC→ GTC1 (1.6)
DeletionGAC, codon 516a 1 (1.6)
InsertionTTC, after codon 513 (Q)1 (1.6)
Total64
  • a Mutation not previously reported.