TABLE 4.

Effect of simultaneous addition of aspirin and PGE2 on biofilm formation by C. albicans GDH 2346

AdditionXTT reduction (%)a by biofilms at 48 h
Aspirin (25 μM)87.7 ± 9.5c
Aspirin (25 μM) + PGE2 (1 nM)106.1 ± 6.0
Aspirin (25 μM) + PGE2 (100 nM)101.3 ± 8.9
Aspirin (50 μM)79.0 ± 7.6b
Aspirin (50 μM) + PGE2 (1 nM)101.2 ± 11.3
Aspirin (50 μM) + PGE2 (100 nM)102.9 ± 7.8
  • a XTT reduction is expressed as a percentage of that of control 48-h biofilms incubated in the absence of aspirin and PGE2. The results are means ± standard errors of the means of two independent experiments carried out with a total of seven replicates. The mean ± standard error of the mean value (A492) for the controls was 2.500 ± 0.112.

  • b Value significantly different at P < 0.001 from that for the control.

  • c Value significantly different at P < 0.01 from that for the control.