TABLE 3.

In vitro lytic effects of catechins against T. cruzi amastigotes in Vero cell cultures

Compound (concn [nM])% of infected cells when drug was addeda:
During the infection2 h postinfection
None100 ± 0.0100 ± 0.0
GCg
    566.00 ± 5.10b68.09 ± 3.55c
    10045.09 ± 2.57c47.05 ± 4.04c
    50022.12 ± 3.04c25.30 ± 1.72c
EGCg
    574.50 ± 6.98d73.70 ± 4.89b
    10052.94 ± 0.76c43.13 ± 4.14c
    50036.42 ± 2.15c34.20 ± 1.00c
  • a The data are expressed as the means ± standard deviations for three independent determinations.

  • b P < 0.005.

  • c P < 0.0005.

  • d P < 0.05.