TABLE 3.

Plasmid-mediated AmpC-type β-lactamases

β-LactamaseSampling locationStrainIsolation date (mo/yr)SourceAssociated resistancescβ-Lactamase bands on IEFdPlasmid designation
ACT-1Medical College of Virginia, RichmondK. pneumoniae12/93UrineCmKmSmSuTmHg5.4, 8.5+pMG278
ACT-1Cabrini Medical Center, New York, N.Y.K. pneumoniae3/94ThroatCmKmSmSuHg5.4, 8.5+pMG249
ACT-1Boston University Medical Center, Boston, Mass.E. coli5/94SputumCmKmSmSuHg5.4, 8.5+pMG245
ACT-1Westchester County Medical Center, Valhalla, N.Y.K. pneumoniae8/94BloodCmKmSmSuHg5.4, 8.5+pMG246
ACT-1Bronx-Lebanon Hospital, New York, N.Y.K. pneumoniae8/94SputumCmKmSmSuHg5.4, 8.5+pMG251
ACT-1St. Elizabeth's Medical Center, Brighton, Mass.K. pneumoniae4/95BloodCmGmKmSmSuTmHg8.5+pMG287
ACT-1VA Medical Center, New York, N.Y.K. pneumoniae1995NAaCmKmSmSuHg5.4, 8.5+pMG260
ACT-1University of Pennsylvania, PhiladelphiaK. pneumoniaeBefb 4/00NACmKmSmSuTmHg5.4, 8.5+pMG279
FOX-5University of Alabama, BirminghamK. pneumoniae9/94UrineCmKmQnSmSuTpHg5.7, 6.0-7.6pMG252
FOX-5Coral Gables, Fla.E. coliBef 1/97UrineCmKmSmSuTpHg5.7, 6.0-7.6pMG280
FOX-5North Florida, Fla.E. coliBef 1/97UrineSuHg6.0-7.6pMG281
FOX-5Dallas, Tex.K. pneumoniaeBef 1/97UrineSuHg6.0-7.6pMG282
FOX-5San Antonio, Tex.K. pneumoniaeBef 1/97UrineCmKmSmSuTpHg5.7, 6.0-7.6pMG283
FOX-5Fort Worth, Tex.K. pneumoniaeBef 1/97UrineCmKmSmSuTpHg5.7, 6.0-7.6pMG284
FOX-5Greensboro, N.C.K. pneumoniaeBef 1/97UrineCmKmSmSuTpHg5.7, 6.0-7.6pMG285
FOX-5Strong Memorial Hospital, Rochester, N.Y.K. pneumoniae3/99BloodCmKmSmSuTpHg5.4, 5.7, 6.0-7.6pMG286
CMY-2University of Michigan, Ann ArborE. coli8/94WoundCmKmSmSuTc5.4, 8.5+pMG250
CMY-2Duke University Medical Center, Durham, N.C.E. coliBef 7/96NACmSmSuTcTpHg8.5+pMG248
DHA-1University of California Medical Center, Los AngelesK. pneumoniae9/94UrineCmKmSmSuTmTpHg6.3, 7.8pMG247
UnknownUniversity of Alabama, BirminghamE. coli6/94UrineGmKmSmSuTcTmTpHg8.5+pMG288
  • a NA, not available.

  • b Bef, before.

  • c Resistance abbreviations: Cm, chloramphenicol; Gm, gentamicin; Hg, mercuric chloride; Km, kanamycin; Qn, quinolone; Sm, streptomycin; Su, sulfonamide; Tc, tetracycline; Tm, tobramycin; Tp, trimethoprim.

  • d IEF, isoelectric focusing.