TABLE 2.

Cumulative radioactivity excretion in urine and feces of caspofungin in rats, rabbits, and monkeys after a single intravenous dosea

SpeciesDose (mg/kg)Collection period (days)% of dose excreted in feces% of dose excreted in urineTotal % of dose excreted
Rat21229.4 ± 2.542.1 ± 1.371.5 ± 1.8
Rabbit52850.8 ± 3.036.0 ± 4.486.8 ± 2.9
Monkey52836.2 ± 0.745.4 ± 0.381.6 ± 1.1
  • a Data are presented as means ± standard deviation for three rats and monkeys and four rabbits.