TABLE 2.

MICs for wild-type isolates of Enterobacteriaceae with carbapenemases

IsolateSpeciesPhenotypeMIC (μg/ml)a
DORMEMIMPERTPTZAZTCAZCPMAMP
CL5761bKlebsiella spp.KPC-3166464>64>64>646464>64
CL5762AbKlebsiella spp.KPC-38321616>64>646464>64
CL5762BbKlebsiella spp.KPC-3326464>64>64>646464>64
CL5763bKlebsiella spp.KPC-364>64>64>64>64>64>6464>64
S6S. marcescensSME-13232>64648320.50.06>64
K4181cK. pneumoniaeIMP-1 porin64>64>64>64>64>64>64>64>64
K4181cK. pneumoniaeIMP-1 porin+16161616>64>64>64>64>64
  • a AMP, ampicillin; AZT, aztreonam; CAZ, ceftazidime; CPM, cefepime; DOR, doripenem; ERT, ertapenem; IMP, imipenem; MEM, meropenem.

  • b Multiple isolates from a single outbreak.

  • c Porin-expressing and deficient variants of the same strain (10).