TABLE 4.

MICs for E. coli strains with plasmid-mediated and cloned β-lactamases

Hostβ-LactamaseMIC (μg/ml)a
DORMEMIMPERTPTZAZTCAZCPMAMP
Plasmid carrying
    J53OXA-10.0150.0150.125<0.00820.060.1250.25>64
    J53OXA-20.0150.0150.125<0.00840.060.250.06>64
    J53OXA-30.030.030.250.01540.1250.5<0.03>64
    J62OXA-100.030.0150.1250.01520.1250.1250.03>64
    J53SHV-10.060.0150.25<0.008320.1250.50.125>64
    J53SHV-20.030.030.1250.25>64163232>64
    J53SHV-3<0.008<0.008<0.03<0.0080.5<0.030.06<0.0364
    J53SHV-40.1250.0310.0158>64>648>64
    J53SHV-50.060.030.50.0154>64>642>64
    J62TEM-10.060.030.50.015640.1250.250.125>64
    J53TEM-20.015<0.008<0.03<0.00810.060.060.06>64
    J62TEM-30.030.0150.1250.01524160.5>64
    J53TEM-60.030.0150.1250.015416>641>64
    J53TEM-90.060.030.250.034>64>6416>64
    J53TEM-100.060.030.1250.015464>642>64
    JM109NMC-A0.51221610.125<0.0364
    DH5-αIMP-10.1250.1250.50.1258<0.03160.2532
Plasmid free
    DH5-αR-<0.0040.03<0.0150.0082<0.030.06<0.032
    J53-1R-0.030.0310.00840.1250.1250.062
    J62-1R-0.060.030.250.0084<0.030.125<0.032
    JM83bR-0.030.030.250.0084<0.030.125<0.032
  • a Abbreviations are as defined in Table 2.

  • b Related to JM109, used as a host for NMC-A β-lactamase.