TABLE 2.

ED50s of three antibiotics in the mouse endogenous bacteremia model

StrainMean ED50 ± SD (mg/kg/day) (95% confidence interval)
CAZIPM-CSCIP
pMS360186.9 ± 28.2 (137.2-266.5)35.1 ± 7.1 (19.8-53.5)10.0 ± 1.7 (6.9-14.8)
pMS363>1,00091.5 ± 24.7 (62.6-456.3)7.1 ± 1.8 (4.3-14.41)