TABLE 2.

List of model parameters and their values

Parameter (at MIC m)VariableValueReference(s)
Birth rateμN0.000250 week−1 2
Death rate in young children (≤2 years old)μ10.000112 week−1 2
Death rate in older children (2-15 years old)μ20.000047 week−1 2
Death rate in adults (≥15 years old)μ30.000295 week−1 2
Duration of treatment1/γ8 days 13, 14
Duration of vaccine immunity dv 15 years
Frequency of treatment in young children (≤2 years old)α11/30 weeks 13, 14
Frequency of treatment in older children (2-15 years old)α21/2 year 13, 14
Frequency of treatment in adults (≥15 years old)α31/4 year 13, 14
Frequency of treatment in vaccinated childrenα41/2 year 7
Duration of carriage1/λ2.2 months 23
Infectious-contact rate between young childrenβ110.60 week−1 person−1 21, 26
Infectious-contact rate between older childrenβ220.25 week−1 person−1 21, 26
Infectious-contact rate between adultsβ330.06 week−1 person−1 21, 26
Infectious-contact rate between young and older childrenβ120.18 week−1 person−1 21, 26
Infectious-contact rate between young children and adultsβ130.30 week−1 person−1 21, 26
Infectious-contact rate between older children and adultsβ230.25 week−1 person−1 21, 26
Probability of decolonization following treatmentσ (m) $$mathtex$$\(\frac{\mathit{m}^{2}}{0.05{+}\mathit{m}^{2}}\)$$mathtex$$ 26