TABLE 2

Comparison of PK parameters for finafloxacin in BALB/c mouse plasma and in human plasmaa

PK parameterOral finafloxacin dose:
Mouse (37.5 mg/kg)Human (800 mg/kg)
t1/21.8910.47
Cmax (μg/ml)7.2411.14
AUC0-∞ (h · μg/ml)11.1229.21