TABLE 1.

Susceptibilities to beta-lactams and erythromycin of pneumococcal isolates from 12 Asian countriesa

CountryNo. of isolatesPenicillinAmoxicillin-clavulanateCefuroximeCeftriaxoneErythromycin
MIC (mg/liter)% I% RMIC (mg/liter)% I% RMIC (mg/liter)% I% RMIC (mg/liter)% I% RMIC (mg/liter)% I% R
90%Range90%Range90%Range90%Range90%Range
Korea314<0.03-49.754.84<0.03-86.59.78<0.03-163.261.31<0.25-43.23.2>320.03->320.080.6
China1112<0.03-819.823.42<0.03-322.77.34<0.03->324.519.81<0.015-160.01.8>32<0.015->320.973.9
Thailand522<0.03-426.926.92<0.03-20.00.08<0.03-81.936.51<0.015-21.90.016<0.015->325.836.5
Taiwan574<0.03-824.638.62<0.03-163.51.88<0.03-88.840.410.03-21.80.0>32<0.015->321.886.0
India770.03<0.03-17.80.0<0.03<0.03-0.50.00.00.12<0.03-80.01.3<0.25<0.015-0.50.00.00.12<0.015-40.01.3
Sri Lanka422<0.03-271.414.32<0.03-20.00.04<0.03-87.119.00.5<0.25-10.00.080.015->322.416.7
Singapore352<0.03-428.617.11<0.03-20.00.04<0.03-85.728.61<0.015-10.00.0>32<0.015->322.940.0
Malaysia442<0.03-49.129.52<0.03-42.30.04<0.03-82.329.51<0.25-160.02.3>320.015->326.834.1
Vietnam6440.03-820.671.48<0.03-1614.322.28<0.03-324.874.22<0.015-49.53.2>320.03->321.692.1
Philippines220.25<0.03-0.2521.30.00.03<0.03-0.060.00.00.25<0.03-0.50.00.00.250.12-0.50.00.016<0.015-164.518.2
Saudi Arabia391<0.03-220.510.30.25<0.03-20.00.04<0.03-162.612.80.5<0.25-10.00.00.12<0.015-320.010.3
Hong Kong1124<0.03-425.343.22<0.03-160.93.68<0.03-1610.050.01<0.015-23.70.0>320.03->320.076.8
    Total6854<0.03-82329.42<0.03-322.64.48<0.03->324.832.41<0.015-161.90.9>16<0.015->161.853.1
  • a Breakpoints for I and R are according to the NCCLS guidelines.