TABLE 1.

Probabilities of increment of the penicillin MIC for pneumococcal strains from one level to another following a genetic event when the colonized host is exposed to antibioticsa

Initial MICProbability with final MIC of:
0.06250.1250.250.512481632
0.06250.19240.32560.32140.06140.00015 · 10−15<10−20<10−20<10−20
0.1250.36780.42780.10480.00034 · 10−14<10−20<10−20<10−20
0.250.58860.21480.00139 · 10−13<10−20<10−20<10−20
0.50.61510.01624 · 10−10<10−20<10−20<10−20
10.39057 · 10−6<10−20<10−20<10−20
20.19951.10−16<10−20<10−20
40.0998<10−20<10−20
80.0499<10−20
160.0249
32
  • a The sum of all probabilities on a given line of the table is equal to 1 minus the probability that the initial MIC remains unchanged.