TABLE 1.

Viability of biofilm cells of Candida species after exposure to flucytosine or fluconazole for 6 or 24 ha

OrganismViability (%)
Flucytosine (6 μg/ml)Fluconazole (24 μg/ml)
6 h24 h6 h24 h
C. albicans GDH 234634.0 ± 2.328.9 ± 0.564.1 ± 1.781.0 ± 1.5
C. albicans GDH 202345.6 ± 1.529.9 ± 1.673.0 ± 2.062.1 ± 1.4
C. albicans GRI 68238.2 ± 2.229.4 ± 0.967.6 ± 1.678.7 ± 2.9
C. glabrata AAHB 1215.8 ± 1.224.2 ± 0.6101.7 ± 1.181.1 ± 1.5
C. krusei71.3 ± 1.366.9 ± 0.574.4 ± 0.647.8 ± 1.2
C. parapsilosis AAHB 47974.9 ± 0.762.1 ± 1.567.4 ± 3.051.1 ± 1.2
C. tropicalis AAHB 7365.0 ± 1.840.5 ± 1.449.6 ± 0.937.7 ± 2.1
  • a Viability is expressed as a percentage of that of control cells incubated under identical conditions in the absence of antifungal agent. The results are means ± standard errors of the means of triplicate determinations.