TABLE 1.

EC50s, EC90s, and EC99s of AQ and DAQ for P. falciparum strains LS-2, LS-3, and LS-1

Compound and strainEC (nM)Cmax (nM)a
50%90%99%
AQ
    LS-20.523.4786.4831.4
    LS-30.237.01343.85
    LS-10.3613.43260.14
DAQ
    LS-20.569.6297.932,507
    LS-30.7729.58546.98
    LS-10.77111.22340.03
  • a Derived from the work of Minzi et al. (19).