TABLE 2.

Comparison of biochemical properties of Ser1-PMP-1, Asp1-PMP-1, and hPF-4

PeptideTissue sourceSequence sourceN-terminal 10-amino-acid sequenceLength (no. of residues)Calculated mass (Da)aActual mass (Da)a
Pre-PMP-1Bone marrowcDNAMSIPEASGAP10611,156NDb
Ser1-PMP-1Resting platelet (acid extract)Amino acidSDDPKESEGD738,0448,053
Asp1-PMP-1Activated platelet (thrombin stimulated)Amino acidDDPKESEGDL727,9577,951
Pre-hPF-4Erythroleukemic cell linecDNAMSSAAGFCAS10110,838ND
hPF-4Activated plateletAmino acidAEAEEDGDLQC707,7657,756
  • a All values are ±0.5%.

  • b ND, not determined.