TABLE 2.

Relative hydrolysis rates of CTX-M-30

Relative hydrolysis rates (%)
SubstrateCf29a pIs of β-lactamases; 5.4, 8.0, and 8.9tCf29b, pI of β-lactamase, 8.0
Cephaloridine100100
Penicillin5859
Cefotaxime1419
CeftazidimeNCcNC
AztreonamNCNC
Cefepime3.45.3
ImipenemNCNC
  • a Clinical isolate of C. freundii.

  • b E. coli transformant of strain C. freundii 29.

  • c NC, not calculated (rates were too low to obtain reliable values).