TABLE 4.

Antibiotic susceptibilities of E. coli transformants with the 75-kb KPC-3-encoding plasmid

AntibioticMIC (μg/ml) for:
DH5αDH5α (KPC-3)aCL 5761
Imipenem0.12 1 8
Meropenem≤0.03 0.25 16
Ceftazidime0.12 16 >32
Ceftriaxone≤0.25 4 128
Aztreonam≤0.25 16 >256
Cefoxitin4 8 256
Amikacin0.5 16 16
Gentamicin0.25 1 16
Streptomycin222
Chloramphenicol88128
Ciprofloxacin0.060.064
Polymyxin B0.50.51
  • a Boldface values indicate significantly increased MICs.