TABLE 1.

MICs for K. ascorbata strains and derived clones

Antibiotic(s)MIC (μg/ml)
K. ascorbata strain:E. coli recombinant clone:E. coli TOP 10F′
6869276KK68C1KK69C1KK276C1
Ampicillin321616>512>512>5122
Ampicillin-clavulanate (2:1)1/0.50.5/0.250.5/0.254/24/28/42/1
Piperacillin444>128>128>1281
Cephalothin161616>1,0241,024>1,0242
Cefoxitin2214482
Cefotaxime0.1250.1250.0631281664≤0.016
Cefotaxime-clavulanatea≤0.032≤0.032≤0.0320.250.0630.25NDb
Ceftazidime0.063≤0.032≤0.0324140.125
Ceftazidime-clavulanatea≤0.032≤0.032≤0.0320.1250.1250.25ND
Cefepime0.016≤0.008≤0.008161160.016
Aztreonam0.063≤0.032≤0.032328320.032
Tetracycline211>128>128128>128
Kanamycin222>128>128>1281
  • a Fixed concentration of lithium clavulanate, 4 μg/ml.

  • b ND, not done.