TABLE 2.

Inhibition of oxygen consumption of A. baumannii at 4 × 108 CFU/ml by CA(1-8)M(1-18) and PXB

Peptide (μM)Oxygen consumption ratea (nmol of O2 108 CFU−1 min−1)
CA(1-8)M(1-18)PXB
Control21.0 ± 1.2 (0.0)21.0 ± 1.2 (0.0)
1.258.3 ± 0.7 (60.4)8.9 ± 0.6 (57.6)
2.55.2 ± 0.5 (75.2)5.8 ± 0.6 (72.3)
5.03.2 ± 0.1 (84.7)5.3 ± 0.4 (74.7)
10.00.3 ± 0.1 (98.5)3.9 ± 0.2 (81.4)
20.0<0.10.5 ± 0.1 (97.6)
  • a Data are expressed as the mean of triplicate samples ± standard deviation. The percentage of inhibition with respect to that of the controls is included in parentheses.