TABLE 3.

Effect of a 70-mg day 1 loading dose on the pharmacokinetics of caspofungin at 50 mg daily

DayGeometric-mean ratio (loading dose/no loading dose) (90% CIs)
AUC0-24C1hC24h
11.70 (1.46, 1.97)1.58 (1.40, 1.78)1.86 (1.34, 2.57)
141.16 (0.96, 1.40)1.14 (0.99, 1.31)1.12 (0.84, 1.48)