TABLE 2.

Spectrum of activity of T-705 against non-influenza virus

Virus and cellT-705 IC50 (μg/ml)a
TypeFamilySpeciesHost cell
DNA Herpesviridae HSV-1Vero>100
Herpesviridae HCMVHEL>100
Adenoviridae AdenovirusA549>100
RNA Picornaviridiae PoliovirusVero4.8
Picornaviridae RhinovirusHeLa23
Paramyxoviridae RSVHEp-241
  • a The values are averages of results from two independent experiments.