TABLE 2.

Summary of agr mutations in GISA strainsa

StrainMutations in:
agrB (aa)agrCbagrA (aa)
Mu50cWTWTI-238-K
Mu3WTWTI-238-K
PC-3WTG-225-DWT
A6298T-177-SWTWT
A5940Nonsense (184)WTNonsense (162)
HIP5836Nonsense (216)
  • a There were no mutations in P2, P3, hld, and agrD. aa, amino acids; WT, wild-type.

  • b C terminus; S. aureus SA502A, -FYSKS; all GISA and hetero-GISA, -FIQKVEIINN; S. epidermidis A086, -FIQKVEILNNIP; and S. lugdunensis, -FVQKVEINNKES.

  • c Mu50 sequences were published by Kuroda et al. (18).