TABLE 3.

Susceptibility of E. faecalis and E. faecium strains to CLI and streptogramins

Organism (no. of isolates)MIC (μg/ml) range (agar dilution)
CLIQ-DDALQuinupristin
E. faecium (68)
    erm(B)+ (49)>2561-168-≥32a≥64a
    erm(B) lacking     (19)
        Clirb (10)4−>2561-162->1288->32
        Clis (9)0.06−0.250.5-14-168-32
E. faecalis (95)
    erm(B)+ (63)128−>2562-64≥32c≥64c
    erm(B) lacking     (32)16−322-64≥32d8-≥64d
  • a Only 18 isolates were tested.

  • b Determined by using NCCLS breakpoints for S. aureus (susceptible, ≤0.5 μg/ml; intermediate, 1-2 μg/ml, resistant, ≥4 μg/ml).

  • c Only nine isolates were tested.

  • d Only 10 isolates were tested.