TABLE 1.

MICs of various antibiotics for strains producing CTX-M-14 β-lactamases

AntibioticaMIC (μg/ml) against:
Clinical isolates (KTC984167)Trans- conjugantCloned strainsJP-995
AMP≥32≥32≥322
LOT≥32≥32≥324
CFX8284
CTX≥64≥64≥64≤0.25
CTX plus CAL≤0.25≤0.25≤0.25≤0.25
CTR≥64≥64≥64≤0.25
CTR plus CAL≤0.5≤0.5≤0.5≤0.5
CPD≥64≥64≥64≤0.5
CPD plus CAL≤0.5≤0.54≤0.5
CAZ2116≤0.25
CAZ plus CAL≤0.25≤0.250.5≤0.25
ATM84≥64≤0.25
IMP≤0.250.50.50.5
GEN>8≤0.5≤0.5≤0.5
AMK4≤2≤2≤2
CIP≤0.06≤0.060.25≤0.06
  • a Abbreviations: AMP, ampicillin; LOT, cephalothin; CFX, cefoxitin; CTX, cefotaxime; CAL, clavulanic acid; CTR, ceftriaxone; CPD, cefpodoxime; CAZ, ceftazidime; ATM, aztreonam; IMP, imipenem; GEN, gentamicin; AMK, amikacin; CIP, ciprofloxacin.