TABLE 1.

Comparison of the MICs of TMP, PMT, PNT, and sulfonamides in RPMI and YNB media for all of the Aspergillus species

MIC parameteraMIC (μg/ml)b
TMPSMXSXTPMTDAPSMTSMPSSXSDZPNT
RPMIYNBRPMIYNBRPMIYNBRPMIYNBRPMIYNBRPMIYNBRPMIYNBRPMIYNBRPMIYNBRPMIYNB
GM>16>16102.4∗61.2116.5∗57.14.5>4>16>16>500336>200108.2>400>400321.6∗123.837.1∗13.2
Range16->168->1640->3202.5->32020->3202.5->3200.25->40.25->4>1616->16125->5000.9->50050->4006.2->400200->40025->40012.5->4000.3->4001->1280.25->128
MIC50>16>16804080404>4>16>16>500>500200100>400>400>400100328
MIC90>16>16320>320320>320>4>4>16>16>500>500>200>200>400>400>400>400>128>128
  • a GM, geometric mean of MIC; MIC50 and MIC90, MICs at which 50 and 90% of the isolates tested, respectively, are inhibited.

  • b ∗, statistically significant difference (P < 0.05) between the GMs in RPMI and YNB.