TABLE 2.

Antifungal susceptibilities of C. albicans strains

Strain (genotype)MIC50 (μg/ml)a of:
FluconazoleItraconazoleMiconazoleVoriconazole
CAF2-1 (ERG3/ERG3 ura3/URA3)0.1250.1250.50.016
CAI-4 (ERG3/ERG3 ura3/ura3)0.250.1250.50.016
CAD1 (erg3/ERG3 ura3/ura3)0.250.50.50.03
CAE3D (erg3/erg3 ura3/ura3)>64>16>16>16
CAE3DU3 (erg3/erg3 ura3/URA3)>64>16>16>16
  • a Antifungal susceptibility was examined by broth microdilution tests following the NCCLS M27-A2 protocol (25), and MIC was determined as the drug concentration required for 50% growth inhibition compared to the drug-free culture at 48 h.