TABLE 2.

Effect of amino acid substitutions in MexF on MIC profiles

StrainMIC (μg/ml)a
TMPCHLCIPNALATM
PT512832-640.1251284
PT6441,0241,0241>2561
PT644ΔF1640.03160.5
PT644ΔF(pMMBN126)128256-5120.125640.5
PT644ΔF(pL4DDAG)1640.03160.5
PT644ΔF(pL4EK)1640.03160.5
PT644ΔF(pL10KE)1640.03160.5
PT644ΔF(pL2EK)16160.03160.5
  • a TMP, trimethoprim; CHL, chloramphenicol; CIP, ciprofloxacin; NAL, nalidixic acid; ATM, aztreonam.