TABLE 4.

Effects of knocking out and presence of multicopy sod genes on the ciprofloxacin sensitivity of E. coli MG1655

Ciprofloxacin concn (ng/ml)% Survival of E. coli (mean ± SD)
MG1655NJ01NJ02MG1655/pDT1.5MG1655/pFeSODMG1655/pSodC2.3
0100 ± 0100 ± 0100 ± 0100 ± 0100 ± 0100 ± 0
1067.3 ± 6.470.2 ± 7.861.5 ± 1.784.0 ± 2.6a90.9 ± 1.9a91.2 ± 10.0a
2041.4 ± 1.336.3 ± 5.732.1 ± 10.135.8 ± 5.249.9 ± 7.939.8 ± 11.5
303.6 ± 1.67.3 ± 1.92.1 ± 1.04.9 ± 0.91.00 ± 0.12.7 ± 0.7
  • a Numerical values that are significantly different from the values for the corresponding controls (P = 0.05).