TABLE 2.

Effects of antioxidants on the diameters of the zone of inhibition produced by fluoroquinolone antibiotics

Antibiotic spotted on the diskConcn (ng)Diam of zone of inhibition (mm) (mean ± SD)
Control+Glutathione (10 mM)
Gatifloxacin2,00012.51 ± 0.418.56 ± 0.48a
40010.82 ± 0.107.58 ± 0.16a
2007.99 ± 0.105.5 ± 0a
405.5 ± 05.5 ± 0
Ofloxacin2,00015.84 ± 0.3810.62 ± 0.34a
40011.68 ± 0.296.63 ± 0.42a
2006.34 ± 0.175.5 ± 0a
405.5 ± 05.5 ± 0
Norfloxacin2,0008.21 ± 0.195.5 ± 0a
4005.5 ± 05.5 ± 0
2005.5 ± 05.5 ± 0
405.5 ± 05.5 ± 0
  • a Numerical values that are significantly different from the values for the corresponding controls (P = 0.05).