TABLE 1.

MICs of CASa

Medium and strainMedian MIC (μg/ml) of CAS
Glucose SC minus uracil caspofungin
    GAL1 URA3 vector control0.5
    GAL1 URA3 truncated SBE2 cDNA2
    GAL1 URA3 full-length SBE2 cDNA2
Galactose SC minus uracil caspofungin
    GAL1 URA3 vector control0.5
    GAL1 URA3 truncated SBE2 cDNA16
    GAL1 URA3 full-length SBE2 cDNA16
  • a The (median) MIC of CAS for the strain transformed by the GAL1URA3 centromeric plasmid pRS 316 (control) and the same strain transformed by the same vector containing the SBE2 cDNA (truncated or full length) on glucose and galactose SC minus uracil CAS liquid (NCCLS M-27A microdilution method).