TABLE 3

Multivariable analysis of factors associated with clinical success at 30 days

FactoraTreatment outcomeP valueMultivariate P value (OR, 95% CI)a
Success (n = 50)Failure (n = 59)
Male (n [%])26 (52)36 (61)0.34
Age (median [range])59 (26–91)61 (25–85)0.49
Diabetes (n [%])13 (26)22 (37)0.21
Chronic liver disease (n [%])11 (22)20 (34)0.17
Chronic respiratory disease (n [%])14 (28)12 (20)0.35
Immunocompromised (n [%])25 (50)29 (49)0.93
Any malignancy (n [%])7 (14)17 (29)0.060.10
Solid-organ transplant recipient (n [%])18 (36)22 (37)0.89
Primary bacteremia (n [%])19 (38)9 (15)0.0070.006 (4.50, 1.53–13.21)
Renal replacement therapy (n [%])6 (12)18 (31)0.020.20
Pitt bacteremia score (median [range])3 (0–9)5 (0–9)0.0030.15
APACHE II score (median [range])17 (7–38)21 (4–36)0.02Excluded for confounding
ICU (n [%])21 (42)35 (59)0.070.24
Treatment with ≥2 active agents (n [%])21 (42)11 (19)0.008Excluded for confounding
Time to active treatment (median [IQR])55.6 (23.5–74.6)66 (34.3–105)0.080.28
Treatment with C-A (n [%])11 (22)2 (3)0.0030.01 (8.64, 1.61–46.39)
  • a CI, confidence interval; ICU, intensive care unit; IQR, interquartile range; OR, odds ratio.