TABLE 1.

Demographic and baseline characteristics

CharacteristicsaValue for dosing group
100 mg t.i.d. (n = 11)200 mg t.i.d. (n = 12)400 mg t.i.d. (n = 10)600 mg b.i.d. (n = 7)900 mg b.i.d. (n = 12)1,200 mg b.i.d. (n = 10)Placebo (n = 16)
Age (yr)37.0 (28.0, 57.0)44.0 (32.0, 64.0)40.0 (32.0, 51.0)36.0 (30.0, 42.0)41.5 (34.0, 53.0)46.0 (28.0, 51.0)40.0 (33.0, 49.0)
Race
    Caucasian7 (64)10 (83)8 (80)7 (100)10 (83)8 (80)14 (88)
    Black2 (18)1 (8)1 (10)01 (8)01 (6)
    Asian00001 (8)00
    Other2 (18)1 (8)1 (10)002 (20)1 (6)
Ht (cm)177.0 (170.0, 185.0)177.5 (167.0, 195.0)181.0 (170.0, 195.0)173.0 (167.0, 188.0)176.5 (144.0, 185.0)171.5 (152.0, 195.0)177.0 (168.0, 193.0)
Wt (kg)79.1 (56.0, 105.5)74.5 (60.9, 83.0)83.0 (61.0, 121.5)74.5 (57.9, 96.2)78.9 (64.7, 101.0)78.9 (68.2, 104.0)81.0 (60.0, 98.2)
CD4+ cell count (cells/mm3)110.0 (34.0, 256.0)132.5 (9.0, 420.0)130.5 (48.0, 308.0)135.0 (7.0, 240.0)98.0 (50.0, 189.0)93.0 (50.0, 189.0)93.5 (40.0, 210.0)
CDC classification
    Asymptomatic01 (8)1 (10)0002 (13)
    Symptomatic3 (27)2 (17)3 (30)1 (14)1 (8)00
    AIDS indicator8 (73)9 (75)6 (60)6 (86)11 (92)10 (100)14 (88)
  • a Values for age, height, weight, and CD4+ cell count are given as median (minimum, maximum). Values for race and CDC classification are given as the number (percentage) of subjects with the particular characteristic.