TABLE 1.

Distribution of ESBLs and AmpC enzymes among 291 E. coli and 282 K. pneumoniae isolates that showed decreased susceptibilities to extended-spectrum cephalosporins from seven medical centers in Taiwan

Species and ESBL or AmpCpI of β-lactamaseNo. of isolates from hospitala:Total no. (%) of isolates
N1N2C1C2C3SE
E. coli78338441181918291
    CMY-2-like9.05704013818127 (43.6)
    CTX-M212847288179158 (54.3)
        CTX-M-1 group8.4 or 8.65419522441 (14.1)
        CTX-M-9 group7.9 or 8.0162428236155117 (40.2)
    SHV-5-like8.21035423027 (9.3)
    Noneb134130214 (4.8)
K. pneumoniae5859781823379282
    CMY-2-like9.0414001010 (3.5)
    DHA-1-like7.81715134031 (11.0)
    CTX-M2121671516105155 (55.0)
        CTX-M-1 group8.4127448148598 (34.8)
        CTX-M-9 group7.9 or 8.091423722057 (20.2)
    SHV34391817324135 (47.9)
        SHV-2-like8.205110209 (3.2)
        SHV-5-like7.634341707304126 (44.7)
    None21110005 (1.8)
  • a The seven medical centers were Triservice General Hospital (N1) and National Taiwan University Hospital (N2) in northern Taiwan, Taichung Veterans General Hospital (C1), China Medical College Hospital (C2), and Chung Shan Medical University Hospital (C3) in central Taiwan, Chi-Mei Medical Center (S) in southern Taiwan, and Buddhist Tzu Chi General Hospital (E) in eastern Taiwan. Hospitals C1 and S are district general hospitals, and the remainder are university hospitals.

  • b ESBLs and AmpC-like enzymes not detected.