TABLE 4.

Effect of polyamine concentrations on MIC of polymyxin B against P. aeruginosa PAO1

PolyamineMIC (μg/ml) of polymyxin B with polyamine (mM) at:a
00.310.621.252.551020
Spermidine0.51224448
Spermine0.52444448
  • a MIC values were determined in Miller-Minton broth in the presence of the indicated concentrations of polyamines.