TABLE 3.

Tissue ratios of [14C]-GAR-936 concentrations according to time of sampling after a 30-min intravenous injection of [14C]-GAR-936

Time of sacrifice (h) after antibiotic infusionDose injected (╬╝Ci) (no. of animals)Ratio of mean radioactivity
Vegetation/ serumCardiac tissue/ serumVegetation/ cardiac tissue
0.5100 (1)1.11.90.6
4190 (2)5.34.81.2
1254 (2)9.315.72.7